Sidhivinayak taimes Shimla। Doctors at the Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, have achieved a significant medical advance in the management of aluminum phosphide (Celphos) poisoning, a condition associated with extremely high mortality in India. In a first-of-its-kind randomized clinical study conducted by the Department of Internal Medicine, researchers demonstrated that the use of intravenous lipid emulsion, when added to standard treatment, substantially improves patient survival and clinical outcomes.
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The findings, published in the international journal European Review of Medical and Pharmacological Sciences, show that early administration of this therapy leads to better hemodynamic stability, quicker correction of metabolic acidosis, and improved recovery even in critically ill patients presenting with shock and cardiac complications. The study was carried out under the guidance of Prof. Sanjay Jain, Dean (Academics) and Head of Internal Medicine, with Dr Mandip Singh Bhatia serving as the principal investigator and Dr Saurabh Chandrabhan Sharda as co-investigator. Supported by funding from PGIMER’s Medical Education and Research Cell, the research highlights an affordable, readily available treatment option that can be implemented even in district and rural hospitals, offering renewed hope in regions such as Punjab, Haryana, and Uttar Pradesh where Celphos poisoning remains a major public-health concern.
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